The 2015 Charleston Southern Buccaneers football team represented Charleston Southern University in the 2015 NCAA Division I FCS football season.
They were led by third-year head coach Jamey Chadwell and played their home games at Buccaneer Field. They were a member of the Big South Conference.
They finished the season 10–3, 6–0 in Big South play to become Big South champions.
They earned the conference’s automatic bid to the FCS Playoffs where they defeated The Citadel in the second round to advance to the quarterfinals where they lost to Jacksonville State.
|September 3||North Greenville*||W 41–14|
|September 12||at Troy*||L 16–44|
|September 17||East Tennessee State*||W 47–7|
|September 26||at The Citadel*||W 33–20|
|October 10||Monmouth||W 37–7|
|October 17||at Presbyterian||W 10–7|
|October 24||at Gardner–Webb||W 34–0|
|October 31||No. 2 Coastal Carolina||W 33–25|
|November 7||at Kennesaw State||W 28–14|
|November 14||Liberty||W 31–24|
|November 21||at No. 3 (FBS) Alabama*||L 6–56|
|December 5||No. 18 The Citadel*||W 14–6|
|December 11||at No. 1 Jacksonville State*||L 38–58|