The Ohio River is a 981-mile (1,579 km) long river in the United States. It is located at the boundary of the Midwestern and Southern United States, flowing southwesterly from far-western Pennsylvania south of Lake Erie to its mouth on the Mississippi River at the southern tip of Illinois.
It is the third largest river by discharge volume in the United States and the largest tributary by volume of the north-south flowing Mississippi River that divides the eastern from western United States.
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