Rivaroxaban

Rivaroxaban, sold under the name Xarelto among others, is an anticoagulant medication ( thinner) used to treat and prevent clots.

Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent clots in atrial fibrillation and following hip or knee surgery. It is taken by mouth.

Common side effects include bleeding.

Other serious side effects may include spinal hematoma and anaphylaxis.

It is unclear if use in pregnancy and breastfeeding is safe.

Compared to warfarin it has fewer interactions with other medications.

It works by blocking the activity of the clotting factor Xa.

Rivaroxaban was patented in 2007 and approved for medical use in the in 2011.

In the , it will not be available as a generic medication until 2024.

It is on the World Health Organization’s List of Essential Medicines.

In 2019, it was the 91st most commonly prescribed medication in the , with more than 8 million prescriptions.