Stone

HMGN

HMGN (High Mobility Group Nucleosome-binding) proteins are members of the broader class of high mobility group (HMG) chromosomal proteins that are involved in regulation of transcription, replication, recombination, and DNA repair. HMGN1 and HMGN2 (initially designated HMG-14 and HMG-17 respectively) were discovered by E.W. Johns research group in the early 1970s. HMGN3, HMGN4, and HMGN5 were discovered later and are less abundant. HMGNs are nucleosome binding proteins that […]

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Tool

A tool is an object that can extend an individual’s ability to modify features of the surrounding environment. Although many animals use simple tools, only human beings, whose use of stone tools dates back hundreds of millennia, have been observed using tools to make other tools. Early tools, made of such materials as stone, bone, and wood, were used for preparation

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